Sickle Cell Haemoglobinopathy is a genetically transmitted disease resulting from a defect in beta chain of haemoglobin where glutamic acid at position six is replaced by valine. Extensive research has revealed the aetiopathogenesis of the disease and made accurate laboratory diagnosis feasible. Sickle Cell Haemoglobinopathy is highly prevalent in Central India in the scheduled tribes and scheduled castes. This monogram is the culmination of the extensive research of last two and a half decades. It deals with the historical aspects aetiopathogenesis radiological features anthropological measurements and then in detail about individual skeletal involvement in Sickle Cell Haemoglobinopathy. This book will be of use to Orthopaedic Surgeons Physicians Paediatricians and Radiologists alike in recognising the patients understanding the disease process and in effective management. The main aim of the monogram is to present a precise and concise description of all aspects of the orthopaedic manifestations of the disease that will be of help to medical professionals to offer the patients of Sickle Cell Haemoglobinopathy a better prognosis.
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Manipal Manual of Medical Physiology